Dose-Dependent Activity of Pyrazinamide in Animal Models of Intracellular and Extracellular Tuberculosis Infections

Recent in vitro pharmacokinetic data suggest that the currently recommended dose of pyrazinamide may be suboptimal for killing intracellular bacilli in humans. We evaluated a range of pyrazinamide doses against intracellular and extracellular Mycobacterium tuberculosis in chronically infected mice a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ahmad, Zahoor, Fraig, Mostafa M., Bisson, Gregory P., Nuermberger, Eric L., Grosset, Jacques H., Karakousis, Petros C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2011
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067197/
https://ncbi.nlm.nih.gov/pubmed/21282447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01524-10
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