Contribution of Moxifloxacin or Levofloxacin in Second-Line Regimens with or without Continuation of Pyrazinamide in Murine Tuberculosis

Rationale: High-dose levofloxacin (L) (1,000 mg) was as active as moxifloxacin (M) (400 mg) in an early bactericidal activity trial, suggesting these fluoroquinolones could be used interchangeably. Whether pyrazinamide (Z) contributes sterilizing activity beyond the first 2 months in fluoroquinolone...

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Bibliografiske detaljer
Main Authors: Ahmad, Zahoor, Tyagi, Sandeep, Minkowski, Austin, Peloquin, Charles A., Grosset, Jacques H., Nuermberger, Eric L.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2013
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735243/
https://ncbi.nlm.nih.gov/pubmed/23593945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201212-2328OC
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