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Contribution of Moxifloxacin or Levofloxacin in Second-Line Regimens with or without Continuation of Pyrazinamide in Murine Tuberculosis

Rationale: High-dose levofloxacin (L) (1,000 mg) was as active as moxifloxacin (M) (400 mg) in an early bactericidal activity trial, suggesting these fluoroquinolones could be used interchangeably. Whether pyrazinamide (Z) contributes sterilizing activity beyond the first 2 months in fluoroquinolone...

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Detalhes bibliográficos
Main Authors: Ahmad, Zahoor, Tyagi, Sandeep, Minkowski, Austin, Peloquin, Charles A., Grosset, Jacques H., Nuermberger, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735243/
https://ncbi.nlm.nih.gov/pubmed/23593945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201212-2328OC
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