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Activity of the Fluoroquinolone DC-159a in the Initial and Continuation Phases of Treatment of Murine Tuberculosis

DC-159a is a new fluoroquinolone with more potent in vitro activity than available fluoroquinolones against both drug-susceptible and fluoroquinolone-resistant Mycobacterium tuberculosis. Here, we report that DC-159a displays pharmacokinetics similar to those of moxifloxacin yet is more active than...

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Detalhes bibliográficos
Main Authors: Ahmad, Zahoor, Minkowski, Austin, Peloquin, Charles A., Williams, Kathy N., Mdluli, Khisimuzi E., Grosset, Jacques H., Nuermberger, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067133/
https://ncbi.nlm.nih.gov/pubmed/21282421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01514-10
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