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Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis

New regimens based on two or more novel agents are sought in order to shorten or simplify the treatment of both drug-susceptible and drug-resistant forms of tuberculosis. PA-824 is a nitroimidazo-oxazine now in phase II trials and has shown significant early bactericidal activity alone and in combin...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Tasneen, Rokeya, Williams, Kathy, Amoabeng, Opokua, Minkowski, Austin, Mdluli, Khisimuzi E., Upton, Anna M., Nuermberger, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291340/
https://ncbi.nlm.nih.gov/pubmed/25331697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03822-14
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