Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis

New regimens based on two or more novel agents are sought in order to shorten or simplify the treatment of both drug-susceptible and drug-resistant forms of tuberculosis. PA-824 is a nitroimidazo-oxazine now in phase II trials and has shown significant early bactericidal activity alone and in combin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Tasneen, Rokeya, Williams, Kathy, Amoabeng, Opokua, Minkowski, Austin, Mdluli, Khisimuzi E., Upton, Anna M., Nuermberger, Eric L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291340/
https://ncbi.nlm.nih.gov/pubmed/25331697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03822-14
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