In Vitro and In Vivo Activities of the Nitroimidazole TBA-354 against Mycobacterium tuberculosis

Nitroimidazoles are a promising new class of antitubercular agents. The nitroimidazo-oxazole delamanid (OPC-67683, Deltyba) is in phase III trials for the treatment of multidrug-resistant tuberculosis, while the nitroimidazo-oxazine PA-824 is entering phase III for drug-sensitive and drug-resistant...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Upton, A. M., Cho, S., Yang, T. J., Kim, Y., Wang, Y., Lu, Y., Wang, B., Xu, J., Mdluli, K., Ma, Z., Franzblau, S. G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291341/
https://ncbi.nlm.nih.gov/pubmed/25331696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03823-14
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