Ligand-induced internalization of the orexin OX(1) and cannabinoid CB(1) receptors assessed via N-terminal SNAP and CLIP-tagging

Por Ward, Richard J, Pediani, John D, Milligan, Graeme
Publicado em 2011

Heteromultimerization of Cannabinoid CB(1) Receptor and Orexin OX(1) Receptor Generates a Unique Complex in Which Both Protomers Are Regulated by Orexin A

Por Ward, Richard J., Pediani, John D., Milligan, Graeme
Publicado em 2011

Ligand Regulation of the Quaternary Organization of Cell Surface M(3) Muscarinic Acetylcholine Receptors Analyzed by Fluorescence Resonance Energy Transfer (FRET) Imaging and Homog...

Por Alvarez-Curto, Elisa, Ward, Richard J., Pediani, John D., Milligan, Graeme
Publicado em 2010

Intramolecular Fluorescence Resonance Energy Transfer (FRET) Sensors of the Orexin OX(1) and OX(2) Receptors Identify Slow Kinetics of Agonist Activation

Por Xu, Tian-Rui, Ward, Richard J., Pediani, John D., Milligan, Graeme
Publicado em 2012

Regulation of Oligomeric Organization of the Serotonin 5-Hydroxytryptamine 2C (5-HT(2C)) Receptor Observed by Spatial Intensity Distribution Analysis

Por Ward, Richard J., Pediani, John D., Godin, Antoine G., Milligan, Graeme
Publicado no J Biol Chem (2015)

Real-time monitoring of redox changes in the mammalian endoplasmic reticulum

Por van Lith, Marcel, Tiwari, Shweta, Pediani, John, Milligan, Graeme, Bulleid, Neil J.
Publicado em 2011

Dynamic Regulation of Quaternary Organization of the M(1) Muscarinic Receptor by Subtype-selective Antagonist Drugs

Por Pediani, John D., Ward, Richard J., Godin, Antoine G., Marsango, Sara, Milligan, Graeme
Publicado no J Biol Chem (2016)

The protein kinase C inhibitor, Ro-31-7459, is a potent activator of ERK and JNK MAP kinases in HUVECs and yet inhibits cyclic AMP-stimulated SOCS-3 gene induction through inactiva...

Por Wiejak, Jolanta, Dunlop, Julia, Stoyle, Chloe, Lappin, Gillian, McIlroy, Anna, Pediani, John D., Gao, Shan, Yarwood, Stephen J.
Publicado em 2012

Anti-ganglioside antibody internalization attenuates motor nerve terminal injury in a mouse model of acute motor axonal neuropathy

Por Fewou, Simon N., Rupp, Angie, Nickolay, Lauren E., Carrick, Kathryn, Greenshields, Kay N., Pediani, John, Plomp, Jaap J., Willison, Hugh J.
Publicado em 2012

Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)

Por Alvarez-Curto, Elisa, Prihandoko, Rudi, Tautermann, Christofer S., Zwier, Jurriaan M., Pediani, John D., Lohse, Martin J., Hoffmann, Carsten, Tobin, Andrew B., Milligan, Graeme
Publicado em 2011

Differences in the Signaling Pathways of α(1A)- and α(1B)-Adrenoceptors Are Related to Different Endosomal Targeting

Por Segura, Vanessa, Pérez-Aso, Miguel, Montó, Fermí, Carceller, Elena, Noguera, María Antonia, Pediani, John, Milligan, Graeme, McGrath, Ian Christie, D’Ocon, Pilar
Publicado em 2013

The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Ther...

Por Hudson, Brian D., Shimpukade, Bharat, Mackenzie, Amanda E., Butcher, Adrian J., Pediani, John D., Christiansen, Elisabeth, Heathcote, Helen, Tobin, Andrew B., Ulven, Trond, Milligan, Graeme
Publicado em 2013

Novel Role for Proteinase-activated Receptor 2 (PAR(2)) in Membrane Trafficking of Proteinase-activated Receptor 4 (PAR(4))

Por Cunningham, Margaret R., McIntosh, Kathryn A., Pediani, John D., Robben, Joris, Cooke, Alexandra E., Nilsson, Mary, Gould, Gwyn W., Mundell, Stuart, Milligan, Graeme, Plevin, Robin
Publicado em 2012

The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice

Por Greenshields, Kay N., Halstead, Susan K., Zitman, Femke M.P., Rinaldi, Simon, Brennan, Kathryn M., O’Leary, Colin, Chamberlain, Luke H., Easton, Alistair, Roxburgh, Jennifer, Pediani, John, Furukawa, Koichi, Furukawa, Keiko, Goodyear, Carl S., Plomp, Jaap J., Willison, Hugh J.
Publicado em 2009