Differences in the Signaling Pathways of α(1A)- and α(1B)-Adrenoceptors Are Related to Different Endosomal Targeting

AIMS: To compare the constitutive and agonist-dependent endosomal trafficking of α(1A)- and α(1B-)adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype. METHODS: Using CypHer5 technology and VSV-G epitope tagged α(1A)- and α(1B)-ARs sta...

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Autori principali: Segura, Vanessa, Pérez-Aso, Miguel, Montó, Fermí, Carceller, Elena, Noguera, María Antonia, Pediani, John, Milligan, Graeme, McGrath, Ian Christie, D’Ocon, Pilar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663791/
https://ncbi.nlm.nih.gov/pubmed/23717684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064996
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