Less translational control, more memory

Por Pavitt, Graham D
Publicado em 2013

Identification of Domains and Residues within the ɛ Subunit of Eukaryotic Translation Initiation Factor 2B (eIF2Bɛ) Required for Guanine Nucleotide Exchange Reveals a Novel Activat...

Por Gomez, Edith, Pavitt, Graham D.
Publicado em 2000

New Insights into Translational Regulation in the Endoplasmic Reticulum Unfolded Protein Response

Por Pavitt, Graham D., Ron, David
Publicado em 2012

Translation controlled

Por Pavitt, Graham D, Ashe, Mark P
Publicado em 2008

eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation

Por Jennings, Martin D., Pavitt, Graham D.
Publicado em 2010

eIF5 is a dual function GAP and GDI for eukaryotic translational control

Por Jennings, Martin D, Pavitt, Graham D
Publicado em 2010

A new function and complexity for protein translation initiation factor eIF2B

Por Jennings, Martin D, Pavitt, Graham D
Publicado no Cell Cycle (2014)

Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation

Por Gomez, Edith, Mohammad, Sarah S., Pavitt, Graham D.
Publicado em 2002

Mutations Causing Childhood Ataxia with Central Nervous System Hypomyelination Reduce Eukaryotic Initiation Factor 2B Complex Formation and Activity

Por Richardson, Jonathan P., Mohammad, Sarah S., Pavitt, Graham D.
Publicado em 2004

Identification of Intersubunit Domain Interactions within Eukaryotic Initiation Factor (eIF) 2B, the Nucleotide Exchange Factor for Translation Initiation

Por Reid, Peter J., Mohammad-Qureshi, Sarah S., Pavitt, Graham D.
Publicado em 2012

Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae

Por Dever, Thomas E., Kinzy, Terri Goss, Pavitt, Graham D.
Publicado no Genetics (2016)

Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes

Por Jennings, Martin D, Kershaw, Christopher J, Adomavicius, Tomas, Pavitt, Graham D
Publicado no eLife (2017)

Parallel High-Throughput Automated Assays to Measure Cell Growth and Beta Galactosidase Reporter Gene Expression in the Yeast Saccharomyces cerevisiae

Por Napper, Andrew D., Motlekar, Nuzhat, de Almeida, Rogerio Alves, Pavitt, Graham D.
Publicado no Curr Protoc Chem Biol (2011)

Tight Binding of the Phosphorylated α Subunit of Initiation Factor 2 (eIF2α) to the Regulatory Subunits of Guanine Nucleotide Exchange Factor eIF2B Is Required for Inhibition of Tr...

Por Krishnamoorthy, Thanuja, Pavitt, Graham D., Zhang, Fan, Dever, Thomas E., Hinnebusch, Alan G.
Publicado em 2001

eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine–nucleotide exchange

Por Pavitt, Graham D., Ramaiah, Kolluru V.A., Kimball, Scot R., Hinnebusch, Alan G.
Publicado em 1998

eIF2B promotes eIF5 dissociation from eIF2•GDP to facilitate guanine nucleotide exchange for translation initiation

Por Jennings, Martin D., Zhou, Yu, Mohammad-Qureshi, Sarah S., Bennett, David, Pavitt, Graham D.
Publicado em 2013

Critical Contacts between the Eukaryotic Initiation Factor 2B (eIF2B) Catalytic Domain and both eIF2β and -2γ Mediate Guanine Nucleotide Exchange

Por Mohammad-Qureshi, Sarah S., Haddad, Raphaël, Hemingway, Elizabeth J., Richardson, Jonathan P., Pavitt, Graham D.
Publicado em 2007

Discovery of Chemical Modulators of a Conserved Translational Control Pathway by Parallel Screening in Yeast

Por Motlekar, Nuzhat, de Almeida, Rogerio Alves, Pavitt, Graham D., Diamond, Scott L., Napper, Andrew D.
Publicado em 2009

The Alpha Subunit of Eukaryotic Initiation Factor 2B (eIF2B) Is Required for eIF2-Mediated Translational Suppression of Vesicular Stomatitis Virus

Por Elsby, Rachel, Heiber, Joshua F., Reid, Peter, Kimball, Scot R., Pavitt, Graham D., Barber, Glen N.
Publicado em 2011

eIF2B is a decameric guanine nucleotide exchange factor with a γ(2)ε(2) tetrameric core

Por Gordiyenko, Yuliya, Schmidt, Carla, Jennings, Martin D., Matak-Vinkovic, Dijana, Pavitt, Graham D., Robinson, Carol V.
Publicado em 2014