Загрузка...

eIF2B promotes eIF5 dissociation from eIF2•GDP to facilitate guanine nucleotide exchange for translation initiation

Protein synthesis factor eIF2 delivers initiator tRNA to the ribosome. Two proteins regulate its G-protein cycle: eIF5 has both GTPase-accelerating protein (GAP) and GDP dissociation inhibitor (GDI) functions, and eIF2B is the guanine nucleotide exchange factor (GEF). In this study, we used protein–...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Jennings, Martin D., Zhou, Yu, Mohammad-Qureshi, Sarah S., Bennett, David, Pavitt, Graham D.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877758/
https://ncbi.nlm.nih.gov/pubmed/24352424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.231514.113
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!