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eIF2β is critical for eIF5-mediated GDP-dissociation inhibitor activity and translational control
In protein synthesis translation factor eIF2 binds initiator tRNA to ribosomes and facilitates start codon selection. eIF2 GDP/GTP status is regulated by eIF5 (GAP and GDI functions) and eIF2B (GEF and GDF activities), while eIF2α phosphorylation in response to diverse signals is a major point of tr...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5175340/ https://ncbi.nlm.nih.gov/pubmed/27458202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw657 |
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