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eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
In protein synthesis initiation, the eukaryotic translation initiation factor (eIF) 2 (a G protein) functions in its GTP-bound state to deliver initiator methionyl-tRNA (tRNA(i)(Met)) to the small ribosomal subunit and is necessary for protein synthesis in all cells1,2. Phosphorylation of eIF2 [eIF2...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875157/ https://ncbi.nlm.nih.gov/pubmed/20485439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09003 |
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