eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine–nucleotide exchange

eIF2B is a heteropentameric guanine-nucleotide exchange factor essential for protein synthesis initiation in eukaryotes. Its activity is inhibited in response to starvation or stress by phosphorylation of the α subunit of its substrate, translation initiation factor eIF2, resulting in reduced rates...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Pavitt, Graham D., Ramaiah, Kolluru V.A., Kimball, Scot R., Hinnebusch, Alan G.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1998
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC316533/
https://ncbi.nlm.nih.gov/pubmed/9472020
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires