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Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation

For protein synthesis initiation in eukaryotes, eIF2B is the guanine-nucleotide exchange factor for eIF2. eIF2B is an essential multi-subunit factor and a major target for translational control in both yeast and mammalian cells. It was shown previously that the largest eIF2B subunit, eIF2Bε, is the...

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Hlavní autoři: Gomez, Edith, Mohammad, Sarah S., Pavitt, Graham D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC129037/
https://ncbi.nlm.nih.gov/pubmed/12356745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf515
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