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Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation

For protein synthesis initiation in eukaryotes, eIF2B is the guanine-nucleotide exchange factor for eIF2. eIF2B is an essential multi-subunit factor and a major target for translational control in both yeast and mammalian cells. It was shown previously that the largest eIF2B subunit, eIF2Bε, is the...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Gomez, Edith, Mohammad, Sarah S., Pavitt, Graham D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129037/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12356745/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf515
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