The Alpha Subunit of Eukaryotic Initiation Factor 2B (eIF2B) Is Required for eIF2-Mediated Translational Suppression of Vesicular Stomatitis Virus

Eukaryotic translation initiation factor 2B (eIF2B) is a heteropentameric guanine nucleotide exchange factor that converts protein synthesis initiation factor 2 (eIF2) from a GDP-bound form to the active eIF2-GTP complex. Cellular stress can repress translation initiation by activating kinases capab...

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Detalhes bibliográficos
Main Authors: Elsby, Rachel, Heiber, Joshua F., Reid, Peter, Kimball, Scot R., Pavitt, Graham D., Barber, Glen N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196436/
https://ncbi.nlm.nih.gov/pubmed/21795329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05146-11
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