eIF2B is a decameric guanine nucleotide exchange factor with a γ(2)ε(2) tetrameric core

eIF2B facilitates and controls protein synthesis in eukaryotes by mediating guanine nucleotide exchange on its partner eIF2. We combined mass spectrometry (MS) with chemical cross-linking, surface accessibility measurements and homology modelling to define subunit stoichiometry and interactions with...

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Detalhes bibliográficos
Main Authors: Gordiyenko, Yuliya, Schmidt, Carla, Jennings, Martin D., Matak-Vinkovic, Dijana, Pavitt, Graham D., Robinson, Carol V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046112/
https://ncbi.nlm.nih.gov/pubmed/24852487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4902
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