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eIF2B is a decameric guanine nucleotide exchange factor with a γ(2)ε(2) tetrameric core
eIF2B facilitates and controls protein synthesis in eukaryotes by mediating guanine nucleotide exchange on its partner eIF2. We combined mass spectrometry (MS) with chemical cross-linking, surface accessibility measurements and homology modelling to define subunit stoichiometry and interactions with...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Pub. Group
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046112/ https://ncbi.nlm.nih.gov/pubmed/24852487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4902 |
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