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Critical Contacts between the Eukaryotic Initiation Factor 2B (eIF2B) Catalytic Domain and both eIF2β and -2γ Mediate Guanine Nucleotide Exchange

Diverse guanine nucleotide exchange factors (GEFs) regulate the activity of GTP binding proteins. One of the most complicated pairs is eukaryotic initiation factor 2B (eIF2B) and eIF2, which function during protein synthesis initiation in eukaryotes. We have mutated conserved surface residues within...

詳細記述

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書誌詳細
主要な著者: Mohammad-Qureshi, Sarah S., Haddad, Raphaël, Hemingway, Elizabeth J., Richardson, Jonathan P., Pavitt, Graham D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951959/
https://ncbi.nlm.nih.gov/pubmed/17526738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00495-07
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