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A new function and complexity for protein translation initiation factor eIF2B

eIF2B is a multisubunit protein that is critical for protein synthesis initiation and its control. It is a guanine nucleotide exchange factor (GEF) for its GTP-binding protein partner eIF2. eIF2 binds initiator tRNA to ribosomes and promotes mRNA AUG codon recognition. eIF2B is critical for regulati...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Jennings, Martin D, Pavitt, Graham D
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613454/
https://ncbi.nlm.nih.gov/pubmed/25486352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.948797
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