A Tight-Binding Mode of Inhibition Is Essential for Anti-Human Immunodeficiency Virus Type 1 Virucidal Activity of Nonnucleoside Reverse Transcriptase Inhibitors

Por Motakis, Dimitrios, Parniak, Michael A.
Publicado em 2002

Virion Instability of Human Immunodeficiency Virus Type 1 Reverse Transcriptase (RT) Mutated in the Protease Cleavage Site between RT p51 and the RT RNase H Domain

Por Abram, Michael E., Parniak, Michael A.
Publicado em 2005

In Vitro Microbicidal Activity of the Nonnucleoside Reverse Transcriptase Inhibitor (NNRTI) UC781 against NNRTI-Resistant Human Immunodeficiency Virus Type 1

Por Hossain, Mohammad M., Parniak, Michael A.
Publicado em 2006

Structure–activity relationships in HIV-1 reverse transcriptase revealed by radiation target analysis

Por Sluis-Cremer, Nicolas, Kempner, Ellis, Parniak, Michael A.
Publicado em 2003

Utilization of a Deoxynucleoside Diphosphate Substrate by HIV Reverse Transcriptase

Por Garforth, Scott J., Parniak, Michael A., Prasad, Vinayaka R.
Publicado em 2008

The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage site

Por Abram, Michael E, Sarafianos, Stefan G, Parniak, Michael A
Publicado em 2010

The Effects of RNase H Inhibitors and Nevirapine on the Susceptibility of HIV-1 to AZT and 3TC

Por Davis, Caroline A., Parniak, Michael A., Hughes, Stephen H.
Publicado em 2011

The role of phenylalanine in structure–function relationships of phenylalanine hydroxylase revealed by radiation target analysis

Por Davis, Michael D., Parniak, Michael A., Kaufman, Seymour, Kempner, Ellis
Publicado em 1997

The Thiocarboxanilide Nonnucleoside Inhibitor UC781 Restores Antiviral Activity of 3′-Azido-3′-Deoxythymidine (AZT) against AZT-Resistant Human Immunodeficiency Virus Type 1

Por Borkow, Gadi, Arion, Dominique, Wainberg, Mark A., Parniak, Michael A.
Publicado em 1999

The M184V Mutation in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 Impairs Rescue of Chain-Terminated DNA Synthesis

Por Götte, Matthias, Arion, Dominique, Parniak, Michael A., Wainberg, Mark A.
Publicado em 2000

A thermodynamic study of the cyclodextrin-UC781 inclusion complex using a HPLC method

Por Yang, Haitao, Parniak, Michael A., Hillier, Sharon L., Rohan, Lisa C.
Publicado no J Incl Phenom Macrocycl Chem (2011)

Inhibitors of HIV-1 Reverse Transcriptase—Associated Ribonuclease H Activity

Por Ilina, Tatiana, LaBarge, Krystal, Sarafianos, Stefan G., Ishima, Rieko, Parniak, Michael A.
Publicado em 2012

SITE-DIRECTED MUTAGENESIS IN THE FINGERS SUBDOMAIN OF HIV-1 REVERSE TRANSCRIPTASE REVEALS A SPECIFIC ROLE FOR THE β3-β4 HAIRPIN LOOP IN dNTP...

Por Garforth, Scott J., Kim, Tae Woo, Parniak, Michael A., Kool, Eric T., Prasad, Vinayaka R.
Publicado em 2006

Characterization of Cyclodextrin Inclusion Complexes of the Anti-HIV Non-Nucleoside Reverse Transcriptase Inhibitor UC781

Por Yang, Haitao, Parniak, Michael A., Isaacs, Charles E., Hillier, Sharon L., Rohan, Lisa C.
Publicado em 2008

Structural Basis of the Allosteric Inhibitor Interaction on the HIV-1 Reverse Transcriptase RNase H domain

Por Christen, Martin T., Menon, Lakshmi, Myshakina, Nataliya A., Ahn, Jinwoo, Parniak, Michael A., Ishima, Rieko
Publicado em 2012

Development of a vaginal delivery film containing EFdA, a novel anti-HIV nucleoside reverse transcriptase inhibitor

Por Zhang, Wei, Parniak, Michael A., Sarafianos, Stefan G., Cost, Marilyn R., Rohan, Lisa C.
Publicado em 2013

In vitro transport characteristics of EFdA, a novel nucleoside reverse transcriptase inhibitor using Caco-2 and MDCKII cell monolayers

Por Zhang, Wei, Parniak, Michael A., Sarafianos, Stefan G., Empey, Philip E., Rohan, Lisa C.
Publicado em 2014

The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC

Por Obitte, Nicholas C, Rohan, Lisa C, Adeyeye, Christianah M, Parniak, Michael A, Esimone, Charles O
Publicado em 2013

Structural Integrity of the Ribonuclease H domain in HIV-1 Reverse Transcriptase

Por Slack, Ryan L., Spiriti, Justin, Ahn, Jinwoo, Parniak, Michael A., Zuckerman, Daniel M., Ishima, Rieko
Publicado no Proteins (2015)

Synthesis of Boranoate, Selenoate, and Thioate Analogs of AZTp(4)A and Ap(4)A

Por Han, Qianwei, Sarafianos, Stefan G., Arnold, Eddy, Parniak, Michael A., Gaffney, Barbara L., Jones, Roger A.
Publicado em 2009