A Tight-Binding Mode of Inhibition Is Essential for Anti-Human Immunodeficiency Virus Type 1 Virucidal Activity of Nonnucleoside Reverse Transcriptase Inhibitors

It was previously found that certain nonnucleoside reverse transcriptase inhibitors (NNRTI) possess virucidal activity against human immunodeficiency virus type 1 (HIV-1), and it was suggested that the tight-binding mode of inhibition of reverse transcriptase might be important for this virucidal ac...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Motakis, Dimitrios, Parniak, Michael A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1851-1856.2002
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