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A Tight-Binding Mode of Inhibition Is Essential for Anti-Human Immunodeficiency Virus Type 1 Virucidal Activity of Nonnucleoside Reverse Transcriptase Inhibitors

It was previously found that certain nonnucleoside reverse transcriptase inhibitors (NNRTI) possess virucidal activity against human immunodeficiency virus type 1 (HIV-1), and it was suggested that the tight-binding mode of inhibition of reverse transcriptase might be important for this virucidal ac...

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Sonraí Bibleagrafaíochta
Main Authors: Motakis, Dimitrios, Parniak, Michael A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC127238/
https://ncbi.nlm.nih.gov/pubmed/12019100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1851-1856.2002
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