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Characterization of Cyclodextrin Inclusion Complexes of the Anti-HIV Non-Nucleoside Reverse Transcriptase Inhibitor UC781

The highly potent anti-HIV agent UC781 is being evaluated for use in topical microbicides to prevent HIV transmission. However, UC781 is extremely hydrophobic with poor water solubility, a property that may complicate appropriate formulation of the drug. In this study, we examined the ability of sev...

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Autors principals: Yang, Haitao, Parniak, Michael A., Isaacs, Charles E., Hillier, Sharon L., Rohan, Lisa C.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628202/
https://ncbi.nlm.nih.gov/pubmed/19089644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9070-3
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