Preclinical Safety Assessments of UC781 Anti-Human Immunodeficiency Virus Topical Microbicide Formulations

The nonnucleoside reverse transcriptase inhibitor UC781 is under development as a potential microbicide to prevent sexual transmission of human immunodeficiency virus type 1 (HIV-1). Two gel formulations of UC781 (0.1% and 1.0%) were evaluated in a range of preclinical safety assessments, including...

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Detalhes bibliográficos
Main Authors: Patton, D. L., Sweeney, Y. T. Cosgrove, Balkus, J. E., Rohan, L. C., Moncla, B. J., Parniak, M. A., Hillier, S. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855550/
https://ncbi.nlm.nih.gov/pubmed/17353240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00984-06
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