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The M184V Mutation in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 Impairs Rescue of Chain-Terminated DNA Synthesis

Nucleoside analog chain terminators such as 3′-azido-3′-deoxythymidine (AZT) and 2′,3′-dideoxy-3′-thiacytidine (3TC) represent an important class of drugs that are used in the clinic to inhibit the reverse transcriptase (RT) of human immunodeficiency virus type 1. Recent data have suggested that mut...

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Bibliografische gegevens
Hoofdauteurs: Götte, Matthias, Arion, Dominique, Parniak, Michael A., Wainberg, Mark A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111867/
https://ncbi.nlm.nih.gov/pubmed/10729133
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