A Novel Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutational Pattern Confers Phenotypic Lamivudine Resistance in the Absence of Mutation 184V

We describe a new human immunodeficiency virus type 1 (HIV-1) mutational pattern associated with phenotypic resistance to lamivudine (3TC) in the absence of the characteristic replacement of methionine by valine at position 184 (M184V) of reverse transcriptase. Combined genotypic and phenotypic anal...

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Detalhes bibliográficos
Main Authors: Hertogs, Kurt, Bloor, Stuart, De Vroey, Veronique, van den Eynde, Christel, Dehertogh, Pascale, van Cauwenberge, Anja, Stürmer, Martin, Alcorn, Timothy, Wegner, Scott, van Houtte, Margriet, Miller, Veronica, Larder, Brendan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89727/
https://ncbi.nlm.nih.gov/pubmed/10681319
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