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The M184V Mutation in Reverse Transcriptase Can Delay Reversion of Attenuated Variants of Simian Immunodeficiency Virus

We previously constructed a series of simian immunodeficiency virus (SIV) mutants containing deletions within a 97-nucleotide region of the SIVmac239 untranslated region or leader sequence. However, as is common with live attenuated viruses, several of the mutants exhibited a moderate propensity for...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Whitney, James B., Oliveira, Maureen, Detorio, Mervi, Guan, Yongjun, Wainberg, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136968/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12163615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.17.8958-8962.2002
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