The M184V Mutation in Reverse Transcriptase Can Delay Reversion of Attenuated Variants of Simian Immunodeficiency Virus

We previously constructed a series of simian immunodeficiency virus (SIV) mutants containing deletions within a 97-nucleotide region of the SIVmac239 untranslated region or leader sequence. However, as is common with live attenuated viruses, several of the mutants exhibited a moderate propensity for...

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Hlavní autoři: Whitney, James B., Oliveira, Maureen, Detorio, Mervi, Guan, Yongjun, Wainberg, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136968/
https://ncbi.nlm.nih.gov/pubmed/12163615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.17.8958-8962.2002
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