Pressure of Zidovudine Accelerates the Reversion of Lamivudine Resistance-Conferring M184V Mutation in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1

We cultured lamivudine-resistant human immunodeficiency virus type 1 (HIV-1) variants over an extended period of time in the presence of zidovudine and observed a premature reversion of the resistance-conferring M184V mutation. These data suggest that the presence of ZDV amplifies differences in rep...

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Detalhes bibliográficos
Main Authors: Diallo, Karidia, Oliveira, Maureen, Moisi, Daniela, Brenner, Bluma, Wainberg, Mark A., Götte, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127311/
https://ncbi.nlm.nih.gov/pubmed/12069983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.7.2254-2256.2002
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