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Structural Integrity of the Ribonuclease H domain in HIV-1 Reverse Transcriptase
The mature form of reverse transcriptase (RT) is a heterodimer comprising the intact 66-kDa subunit (p66) and a smaller 51-kDa subunit (p51) that is generated by removal of most of the RNase H (RNH) domain from a p66 subunit by proteolytic cleavage between residues 440/441. Viral infectivity is elim...
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| Publicado no: | Proteins |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509971/ https://ncbi.nlm.nih.gov/pubmed/26061827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24843 |
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