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Interaction of HIV-1 Reverse Transcriptase Ribonuclease H with an Acylhydrazone Inhibitor

HIV-1 reverse transcriptase (RT) is a bi-functional enzyme, having both DNA polymerase (RNA- and DNA-dependent) and ribonuclease H (RNH) activities. HIV-1 RT has been an exceptionally important target for antiretroviral therapeutic development, and nearly half of the current clinically used antiretr...

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Dettagli Bibliografici
Autori principali: Gong, Qingguo, Menon, Lakshmi, Ilina, Tatiana, Miller, Lena G., Ahn, Jinwoo, Parniak, Michael A., Ishima, Rieko
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320797/
https://ncbi.nlm.nih.gov/pubmed/21114787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2010.01052.x
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