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Entire-Dataset Analysis of NMR Fast-Exchange Titration Spectra: a Mg(2+) Titration Analysis for HIV-1 Ribonuclease H Domain
This article communicates our study to elucidate the molecular determinants of weak Mg(2+) interaction with the ribonuclease H (RNH) domain of HIV-1 reverse transcriptase in solution. Since the interaction is weak (a ligand-dissociation constant > 1 mM), non-specific Mg(2+) interaction with the p...
Gardado en:
| Publicado en: | J Phys Chem B |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5850897/ https://ncbi.nlm.nih.gov/pubmed/27973819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b08323 |
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