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The role of phenylalanine in structure–function relationships of phenylalanine hydroxylase revealed by radiation target analysis

The activity of rat liver phenylalanine hydroxylase (PAH; phenylalanine 4-monooxygenase, EC 1.14.16.1) is regulated by interaction with its substrate, phenylalanine, and its coenzyme, BH(4) [tetrahydrobiopterin (6R-dihydroxypropyl-l-erythro-5,6,7,8-tetrahydropterin)]. The structural changes accompan...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Davis, Michael D., Parniak, Michael A., Kaufman, Seymour, Kempner, Ellis
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19540/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.491
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