Ligand modulation of REV-ERBα function resets the peripheral circadian clock in a phasic manner

Por Meng, Qing Jun, McMaster, Andrew, Beesley, Stephen, Lu, Wei Qun, Gibbs, Julie, Parks, Derek, Collins, Jon, Farrow, Stuart, Donn, Rachelle, Ray, David, Loudon, Andrew
Publicado em 2008

Encoded Library Technology Screening of Hepatitis C Virus NS4B Yields a Small-Molecule Compound Series with In Vitro Replicon Activity

Por Arico-Muendel, Christopher, Zhu, Zhengrong, Dickson, Hamilton, Parks, Derek, Keicher, Jesse, Deng, Jianghe, Aquilani, Leah, Coppo, Frank, Graybill, Todd, Lind, Kenneth, Peat, Andrew, Thomson, Michael
Publicado no Antimicrob Agents Chemother (2015)

Structural Analysis of Rev-erbα Bound to NCoR Reveals a Unique Mechanism of Nuclear Receptor-Corepressor Interaction

Por Phelan, Caroline A., Gampe, Robert T., Lambert, Millard H., Parks, Derek J., Montana, Valerie, Bynum, Jane, Broderick, Timothy M., Hu, Xiao, Williams, Shawn P., Nolte, Robert T., Lazar, Mitchell A.
Publicado em 2010

Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B Protein

Por Pouliot, Jeffrey J., Thomson, Michael, Xie, Mi, Horton, Joseph, Johnson, John, Krull, David, Mathis, Amanda, Morikawa, Yoshio, Parks, Derek, Peterson, Richard, Shimada, Takashi, Thomas, Elizabeth, Vamathevan, Jessica, Van Horn, Stephanie, Xiong, Zhiping, Hamatake, Robert, Peat, Andrew J.
Publicado no Antimicrob Agents Chemother (2015)

The Phytoestrogen Coumestrol Is a Naturally Occurring Antagonist of the Human Pregnane X Receptor

Por Wang, Hongwei, Li, Hao, Moore, Linda B., Johnson, Michael D. L., Maglich, Jodi M., Goodwin, Bryan, Ittoop, Olivia R. R., Wisely, Bruce, Creech, Katrina, Parks, Derek J., Collins, Jon L., Willson, Timothy M., Kalpana, Ganjam V., Venkatesh, Madhukumar, Xie, Wen, Cho, Sool Y., Roboz, John, Redinbo, Matthew, Moore, John T., Mani, Sridhar
Publicado no Mol Endocrinol (2008)

Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization

Por Shotwell, J. Brad, Baskaran, Subramanian, Chong, Pek, Creech, Katrina L., Crosby, Renae M., Dickson, Hamilton, Fang, Jing, Garrido, Dulce, Mathis, Amanda, Maung, Jack, Parks, Derek J., Pouliot, Jeffrey J., Price, Daniel J., Rai, Roopa, Seal, John W., Schmitz, Uli, Tai, Vincent W. F., Thomson, Michael, Xie, Mi, Xiong, Zhiping Z., Peat, Andrew J.
Publicado em 2012

A peroxisome proliferator-activated receptor γ ligand inhibits adipocyte differentiation

Por Oberfield, Jennifer L., Collins, Jon L., Holmes, Christopher P., Goreham, Donna M., Cooper, Joel P., Cobb, Jeffery E., Lenhard, James M., Hull-Ryde, Emily A., Mohr, Christopher P., Blanchard, Steven G., Parks, Derek J., Moore, Linda B., Lehmann, Jürgen M., Plunket, Kelli, Miller, Ann B., Milburn, Michael V., Kliewer, Steven A., Willson, Timothy M.
Publicado em 1999