Evaluation of Computational Docking to Identify Pregnane X Receptor Agonists in the ToxCast Database

Por Kortagere, Sandhya, Krasowski, Matthew D., Reschly, Erica J., Venkatesh, Madhukumar, Mani, Sridhar, Ekins, Sean
Publicado em 2010

In Vivo and In Vitro Characterization of a First-in-Class Novel Azole Analog That Targets Pregnane X Receptor Activation

Por Venkatesh, Madhukumar, Wang, Hongwei, Cayer, Julie, Leroux, Melissa, Salvail, Dany, Das, Bhaskar, Wrobel, Jay E., Mani, Sridhar
Publicado em 2011

Novel Yeast-based Strategy Unveils Antagonist Binding Regions on the Nuclear Xenobiotic Receptor PXR

Por Li, Hao, Redinbo, Matthew R., Venkatesh, Madhukumar, Ekins, Sean, Chaudhry, Anik, Bloch, Nicolin, Negassa, Abdissa, Mukherjee, Paromita, Kalpana, Ganjam, Mani, Sridhar
Publicado em 2013

Pregnane X Receptor Regulates Pathogen-Induced Inflammation and Host Defense against an Intracellular Bacterial Infection through Toll-like Receptor 4

Por Qiu, Zhijuan, Cervantes, Jorge L., Cicek, Basak B., Mukherjee, Subhajit, Venkatesh, Madhukumar, Maher, Leigh A., Salazar, Juan C., Mani, Sridhar, Khanna, Kamal M.
Publicado no Sci Rep (2016)

Corrigendum: Pregnane X Receptor Regulates Pathogen-Induced Inflammation and Host Defense against an Intracellular Bacterial Infection through Toll-like Receptor 4

Por Qiu, Zhijuan, Cervantes, Jorge L., Cicek, Basak B., Mukherjee, Subhajit, Venkatesh, Madhukumar, Maher, Leigh A., Salazar, Juan C., Mani, Sridhar, Khanna, Kamal M.
Publicado no Sci Rep (2017)

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

Por Wallace, Bret D., Wang, Hongwei, Lane, Kimberly T., Scott, John E., Orans, Jillian, Koo, Ja Seol, Venkatesh, Madhukumar, Jobin, Christian, Yeh, Li-An, Mani, Sridhar, Redinbo, Matthew R.
Publicado em 2010

Alleviation of Gut Inflammation by Cdx2/Pxr Pathway in a Mouse Model of Chemical Colitis

Por Dou, Wei, Mukherjee, Subhajit, Li, Hao, Venkatesh, Madhukumar, Wang, Hongwei, Kortagere, Sandhya, Peleg, Ariel, Chilimuri, Sridhar S., Wang, Zheng-Tao, Feng, Ying, Fearon, Eric R., Mani, Sridhar
Publicado em 2012

Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice

Por Wang, Hongwei, Venkatesh, Madhukumar, Li, Hao, Goetz, Regina, Mukherjee, Subhajit, Biswas, Arunima, Zhu, Liang, Kaubisch, Andreas, Wang, Lei, Pullman, James, Whitney, Kathleen, Kuro-o, Makoto, Roig, Andres I., Shay, Jerry W., Mohammadi, Moosa, Mani, Sridhar
Publicado em 2011

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

Por Venkatesh, Madhukumar, Mukherjee, Subhajit, Wang, Hongwei, Li, Hao, Sun, Katherine, Benechet, Alaxandre P., Qiu, Zhijuan, Maher, Leigh, Redinbo, Matthew R., Phillips, Robert S., Fleet, James C., Kortagere, Sandhya, Mukherjee, Paromita, Fasano, Alessio, Le Ven, Jessica, Nicholson, Jeremy K., Dumas, Marc E., Khanna, Kamal M., Mani, Sridhar
Publicado em 2014

The Phytoestrogen Coumestrol Is a Naturally Occurring Antagonist of the Human Pregnane X Receptor

Por Wang, Hongwei, Li, Hao, Moore, Linda B., Johnson, Michael D. L., Maglich, Jodi M., Goodwin, Bryan, Ittoop, Olivia R. R., Wisely, Bruce, Creech, Katrina, Parks, Derek J., Collins, Jon L., Willson, Timothy M., Kalpana, Ganjam V., Venkatesh, Madhukumar, Xie, Wen, Cho, Sool Y., Roboz, John, Redinbo, Matthew, Moore, John T., Mani, Sridhar
Publicado no Mol Endocrinol (2008)