Structural Analysis of Rev-erbα Bound to NCoR Reveals a Unique Mechanism of Nuclear Receptor-Corepressor Interaction

Repression by the nuclear receptor (NR) Rev-erbα plays an integral role in the core molecular circadian clock. We report the crystal structure of a Nuclear Receptor Corepressor (NCoR) Interaction Domain 1 (ID1) peptide bound to truncated human Rev-erbα ligand binding domain (LBD). The ID1 peptide fo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Phelan, Caroline A., Gampe, Robert T., Lambert, Millard H., Parks, Derek J., Montana, Valerie, Bynum, Jane, Broderick, Timothy M., Hu, Xiao, Williams, Shawn P., Nolte, Robert T., Lazar, Mitchell A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719173/
https://ncbi.nlm.nih.gov/pubmed/20581824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1860
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker