Pin1 promotes GR transactivation by enhancing recruitment to target genes

par Poolman, Toryn M., Farrow, Stuart N., Matthews, Laura, Loudon, Andrew S., Ray, David W.
Publié 2013

DR3 Regulates Negative Selection during Thymocyte Development

par Wang, Eddie C. Y., Thern, Anette, Denzel, Angela, Kitson, Jeremy, Farrow, Stuart N., Owen, Michael J.
Publié 2001

Transcriptomic analyses of murine resolution-phase macrophages

par Stables, Melanie J., Shah, Sonia, Camon, Evelyn B., Lovering, Ruth C., Newson, Justine, Bystrom, Jonas, Farrow, Stuart, Gilroy, Derek W.
Publié dans Blood (2011)

A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function

par Trebble, Peter J., Woolven, James M., Saunders, Ken A., Simpson, Karen D., Farrow, Stuart N., Matthews, Laura C., Ray, David W.
Publié 2013

Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP

par Bystrom, Jonas, Evans, Ian, Newson, Justine, Stables, Melanie, Toor, Iqbal, van Rooijen, Nico, Crawford, Mark, Colville-Nash, Paul, Farrow, Stuart, Gilroy, Derek W.
Publié 2008

Inhibition of Lipopolysaccharide-Stimulated Chronic Obstructive Pulmonary Disease Macrophage Inflammatory Gene Expression by Dexamethasone and the p38 Mitogen-Activated Protein K...

par Kent, Lauren M., Smyth, Lucy J. C., Plumb, Jonathan, Clayton, Chris L., Fox, Steve M., Ray, David W., Farrow, Stuart N., Singh, Dave
Publié 2009

Ligand modulation of REV-ERBα function resets the peripheral circadian clock in a phasic manner

par Meng, Qing Jun, McMaster, Andrew, Beesley, Stephen, Lu, Wei Qun, Gibbs, Julie, Parks, Derek, Collins, Jon, Farrow, Stuart, Donn, Rachelle, Ray, David, Loudon, Andrew
Publié 2008

Death Receptor 3 regulates distinct pathological attributes of acute versus chronic murine allergic lung inflammation

par Singh, Ravinder Kaur, Perks, William Victor, Twohig, Jason Peter, Kidd, Emma J., Broadley, Kenneth, Farrow, Stuart N., Williams, Anwen Sian, Taylor, Philip Russel, Wang, Eddie Chung Yern
Publié dans Cell Immunol (2017)

The Methyltransferase WBSCR22/Merm1 Enhances Glucocorticoid Receptor Function and Is Regulated in Lung Inflammation and Cancer

par Jangani, Maryam, Poolman, Toryn M., Matthews, Laura, Yang, Nan, Farrow, Stuart N., Berry, Andrew, Hanley, Neil, Williamson, Andrew J. K., Whetton, Anthony D., Donn, Rachelle, Ray, David W.
Publié 2014

A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2

par Vardaka, Panagiota, Lozano, Teresa, Bot, Christopher, Ellery, Jonathan, Whiteside, Sarah K., Imianowski, Charlotte J., Farrow, Stuart, Walker, Simon, Okkenhaug, Hanneke, Yang, Jie, Okkenhaug, Klaus, Kuo, Paula, Roychoudhuri, Rahul
Publié dans Sci Rep (2020)

The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines

par Gibbs, Julie E., Blaikley, John, Beesley, Stephen, Matthews, Laura, Simpson, Karen D., Boyce, Susan H., Farrow, Stuart N., Else, Kathryn J., Singh, Dave, Ray, David W., Loudon, Andrew S. I.
Publié 2012

An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action

par Gibbs, Julie, Ince, Louise, Matthews, Laura, Mei, Junjie, Bell, Thomas, Yang, Nan, Saer, Ben, Begley, Nicola, Poolman, Toryn, Pariollaud, Marie, Farrow, Stuart, Demayo, Francesco, Hussell, Tracy, Worthen, G Scott, Ray, David, Loudon, Andrew
Publié dans Nat Med (2014)

PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis

par Martin, Katherine, Pritchett, James, Llewellyn, Jessica, Mullan, Aoibheann F., Athwal, Varinder S., Dobie, Ross, Harvey, Emma, Zeef, Leo, Farrow, Stuart, Streuli, Charles, Henderson, Neil C., Friedman, Scott L., Hanley, Neil A., Piper Hanley, Karen
Publié dans Nat Commun (2016)

Optimized Chemical Probes for REV-ERBα

par Trump, Ryan P., Bresciani, Stefano, Cooper, Anthony W. J., Tellam, James P., Wojno, Justyna, Blaikley, John, Orband-Miller, Lisa A., Kashatus, Jennifer A., Dawson, Helen C., Loudon, Andrew, Ray, David, Grant, Daniel, Farrow, Stuart N., Willson, Timothy M., Tomkinson, Nicholas C. O.
Publié dans J Med Chem (2013)

Serum and Glucocorticoid Regulated Kinase 1 (SGK1) Regulates Neutrophil Clearance During Inflammation Resolution

par Burgon, Joseph, Robertson, Anne L., Sadiku, Pranvera, Wang, Xingang, Hooper-Greenhill, Edward, Prince, Lynne R., Walker, Paul, Hoggett, Emily E., Ward, Jonathan R., Farrow, Stuart N., Zuercher, William J., Jeffrey, Philip, Savage, Caroline O., Ingham, Philip W., Hurlstone, Adam F., Whyte, Moira K. B., Renshaw, Stephen A.
Publié 2014

Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen

par Robertson, Anne L., Ogryzko, Nikolay V., Henry, Katherine M., Loynes, Catherine A., Foulkes, Matthew J., Meloni, Marco M., Wang, Xingang, Ford, Christopher, Jackson, Malcolm, Ingham, Philip W., Wilson, Heather L., Farrow, Stuart N., Solari, Roberto, Flower, Roderick J., Jones, Simon, Whyte, Moira K. B., Renshaw, Stephen A.
Publié dans Dis Model Mech (2016)

Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy

par Matthews, Laura C., Berry, Andrew A., Morgan, David J., Poolman, Toryn M., Bauer, Kerstin, Kramer, Frederike, Spiller, David G., Richardson, Rachel V., Chapman, Karen E., Farrow, Stuart N., Norman, Michael R., Williamson, Andrew J. K., Whetton, Anthony D., Taylor, Stephen S., Tuckermann, Jan P., White, Michael R. H., Ray, David W.
Publié dans Proc Natl Acad Sci U S A (2015)

A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

par Robertson, Anne L., Holmes, Geoffrey R., Bojarczuk, Aleksandra N., Burgon, Joseph, Loynes, Catherine A., Chimen, Myriam, Sawtell, Amy K., Hamza, Bashar, Willson, Joseph, Walmsley, Sarah R., Anderson, Sean R., Coles, Mark C., Farrow, Stuart N., Solari, Roberto, Jones, Simon, Prince, Lynne R., Irimia, Daniel, Rainger, G. Ed, Kadirkamanathan, Visakan, Whyte, Moira K. B., Renshaw, Stephen A.
Publié dans Sci Transl Med (2014)