Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen

Neutrophils are essential for host defence and are recruited to sites of inflammation in response to tissue injury or infection. For inflammation to resolve, these cells must be cleared efficiently and in a controlled manner, either by apoptosis or reverse migration. If the inflammatory response is...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Robertson, Anne L., Ogryzko, Nikolay V., Henry, Katherine M., Loynes, Catherine A., Foulkes, Matthew J., Meloni, Marco M., Wang, Xingang, Ford, Christopher, Jackson, Malcolm, Ingham, Philip W., Wilson, Heather L., Farrow, Stuart N., Solari, Roberto, Flower, Roderick J., Jones, Simon, Whyte, Moira K. B., Renshaw, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920152/
https://ncbi.nlm.nih.gov/pubmed/27079522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.024935
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