Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library

Cell migration is fundamental to the inflammatory response, but uncontrolled cell migration and excess recruitment of neutrophils and other leukocytes can cause damage to the tissue. Here we describe the use of an in vivo model – the Tg(mpx:GFP)(i114) zebrafish line, in which neutrophils are labelle...

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Dettagli Bibliografici
Autori principali: Wang, Xingang, Robertson, Anne L., Li, Jingyu, Chai, Ruth Jinfen, Haishan, Wang, Sadiku, Pranvera, Ogryzko, Nikolay V., Everett, Martin, Yoganathan, Kanagasundaram, Luo, Hongbo Robert, Renshaw, Stephen A., Ingham, Philip W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Limited 2014
Soggetti:
Research Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882058/
https://ncbi.nlm.nih.gov/pubmed/24291762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012047
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