Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library

Cell migration is fundamental to the inflammatory response, but uncontrolled cell migration and excess recruitment of neutrophils and other leukocytes can cause damage to the tissue. Here we describe the use of an in vivo model – the Tg(mpx:GFP)(i114) zebrafish line, in which neutrophils are labelle...

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מידע ביבליוגרפי
Main Authors: Wang, Xingang, Robertson, Anne L., Li, Jingyu, Chai, Ruth Jinfen, Haishan, Wang, Sadiku, Pranvera, Ogryzko, Nikolay V., Everett, Martin, Yoganathan, Kanagasundaram, Luo, Hongbo Robert, Renshaw, Stephen A., Ingham, Philip W.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Company of Biologists Limited 2014
נושאים:
Research Report
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882058/
https://ncbi.nlm.nih.gov/pubmed/24291762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012047
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