Hypoxia and the regulation of myeloid cell metabolic imprinting: consequences for the inflammatory response

door Sadiku, Pranvera, Walmsley, Sarah R
Gepubliceerd in EMBO Rep (2019)

Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library

door Wang, Xingang, Robertson, Anne L., Li, Jingyu, Chai, Ruth Jinfen, Haishan, Wang, Sadiku, Pranvera, Ogryzko, Nikolay V., Everett, Martin, Yoganathan, Kanagasundaram, Luo, Hongbo Robert, Renshaw, Stephen A., Ingham, Philip W.
Gepubliceerd in 2014

Serum and Glucocorticoid Regulated Kinase 1 (SGK1) Regulates Neutrophil Clearance During Inflammation Resolution

door Burgon, Joseph, Robertson, Anne L., Sadiku, Pranvera, Wang, Xingang, Hooper-Greenhill, Edward, Prince, Lynne R., Walker, Paul, Hoggett, Emily E., Ward, Jonathan R., Farrow, Stuart N., Zuercher, William J., Jeffrey, Philip, Savage, Caroline O., Ingham, Philip W., Hurlstone, Adam F., Whyte, Moira K. B., Renshaw, Stephen A.
Gepubliceerd in 2014

Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression

door Jones, Robert, McDonald, Kate E., Willson, Joseph A., Ghesquière, Bart, Sammut, David, Daniel, Eleni, Harris, Alison J., Lewis, Amy, Thompson, A. A. Roger, Dickinson, Rebecca S., Plant, Tracie, Murphy, Fiona, Sadiku, Pranvera, Keevil, Brian G., Carmeliet, Peter, Whyte, Moira K. B., Newell-Price, John, Walmsley, Sarah R.
Gepubliceerd in Blood (2016)

Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism

door Watts, Emily R., Howden, Andrew J.M., Morrison, Tyler, Sadiku, Pranvera, Hukelmann, Jens, von Kriegsheim, Alex, Ghesquiere, Bart, Murphy, Fiona, Mirchandani, Ananda S., Humphries, Duncan C., Grecian, Robert, Ryan, Eilise M., Coelho, Patricia, Blanco, Gio Rodriguez, Plant, Tracie M., Dickinson, Rebecca S., Finch, Andy, Vermaelen, Wesley, Cantrell, Doreen A., Whyte, Moira K., Walmsley, Sarah R.
Gepubliceerd in J Clin Invest (2021)

IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo

door Harris, Alison J., Mirchandani, Ananda S., Lynch, Ruairi W., Murphy, Fiona, Delaney, Liam, Small, Donna, Coelho, Patricia, Watts, Emily R., Sadiku, Pranvera, Griffith, David, Dickinson, Rebecca S., Clark, Eilidh, Willson, Joseph A., Morrison, Tyler, Mazzone, Massimilliano, Carmeliet, Peter, Ghesquiere, Bart, O’Kane, Cecilia, McAuley, Danny, Jenkins, Steve J., Whyte, Moira K. B., Walmsley, Sarah R.
Gepubliceerd in Am J Respir Crit Care Med (2019)

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

door Sadiku, Pranvera, Willson, Joseph A., Dickinson, Rebecca S., Murphy, Fiona, Harris, Alison J., Lewis, Amy, Sammut, David, Mirchandani, Ananda S., Ryan, Eilise, Watts, Emily R., Thompson, A.A. Roger, Marriott, Helen M., Dockrell, David H., Taylor, Cormac T., Schneider, Martin, Maxwell, Patrick H., Chilvers, Edwin R., Mazzone, Massimilliano, Moral, Veronica, Pugh, Chris W., Ratcliffe, Peter J., Schofield, Christopher J., Ghesquiere, Bart, Carmeliet, Peter, Whyte, Moira K.B., Walmsley, Sarah R.
Gepubliceerd in J Clin Invest (2017)

NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease

door Ryan, Eilise M., Sadiku, Pranvera, Coelho, Patricia, Watts, Emily R., Zhang, Ailiang, Howden, Andrew J. M., Sanchez-Garcia, Manuel A., Bewley, Martin, Cole, Joby, McHugh, Brian J., Vermaelen, Wesley, Ghesquiere, Bart, Carmeliet, Peter, Rodriguez Blanco, Giovanny, Von Kriegsheim, Alex, Sanchez, Yolanda, Rumsey, William, Callahan, James F., Cooper, George, Parkinson, Nicholas, Baillie, Kenneth, Cantrell, Doreen A., McCafferty, John, Choudhury, Gourab, Singh, Dave, Dockrell, David H., Whyte, Moira K. B., Walmsley, Sarah R.
Gepubliceerd in Am J Respir Crit Care Med (2023)

­­­­­­­A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS­­­

door Reyes, Leila, A. Sanchez-Garcia, Manuel, Morrison, Tyler, Howden, Andy J. M., Watts, Emily R., Arienti, Simone, Sadiku, Pranvera, Coelho, Patricia, Mirchandani, Ananda S., Zhang, Ailiang, Hope, David, Clark, Sarah K., Singleton, Jo, Johnston, Shonna, Grecian, Robert, Poon, Azin, McNamara, Sarah, Harper, Isla, Fourman, Max Head, Brenes, Alejandro J., Pathak, Shalini, Lloyd, Amy, Blanco, Giovanny Rodriguez, von Kriegsheim, Alex, Ghesquiere, Bart, Vermaelen, Wesley, Cologna, Camila T., Dhaliwal, Kevin, Hirani, Nik, Dockrell, David H., Whyte, Moira K. B., Griffith, David, Cantrell, Doreen A., Walmsley, Sarah R.
Gepubliceerd in Wellcome Open Res (2021)

Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis

door Sadiku, Pranvera, Willson, Joseph A., Ryan, Eilise M., Sammut, David, Coelho, Patricia, Watts, Emily R., Grecian, Robert, Young, Jason M., Bewley, Martin, Arienti, Simone, Mirchandani, Ananda S., Sanchez Garcia, Manuel A., Morrison, Tyler, Zhang, Ailing, Reyes, Leila, Griessler, Tobias, Jheeta, Privjyot, Paterson, Gordon G., Graham, Christopher J., Thomson, John P., Baillie, Kenneth, Thompson, A.A. Roger, Morgan, Jessie-May, Acosta-Sanchez, Abel, Dardé, Veronica M., Duran, Jordi, Guinovart, Joan J., Rodriguez-Blanco, Gio, Von Kriegsheim, Alex, Meehan, Richard R., Mazzone, Massimiliano, Dockrell, David H., Ghesquiere, Bart, Carmeliet, Peter, Whyte, Moira K.B., Walmsley, Sarah R.
Gepubliceerd in Cell Metab (2021)

Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis

door Sadiku, Pranvera, Willson, Joseph A., Ryan, Eilise M., Sammut, David, Coelho, Patricia, Watts, Emily R., Grecian, Robert, Young, Jason M., Bewley, Martin, Arienti, Simone, Mirchandani, Ananda S., Sanchez Garcia, Manuel A., Morrison, Tyler, Zhang, Ailing, Reyes, Leila, Griessler, Tobias, Jheeta, Privjyot, Paterson, Gordon G., Graham, Christopher J., Thomson, John P., Baillie, Kenneth, Thompson, A.A. Roger, Morgan, Jessie-May, Acosta-Sanchez, Abel, Dardé, Veronica M., Duran, Jordi, Guinovart, Joan J., Rodriguez-Blanco, Gio, Von Kriegsheim, Alex, Meehan, Richard R., Mazzone, Massimiliano, Dockrell, David H., Ghesquiere, Bart, Carmeliet, Peter, Whyte, Moira K.B., Walmsley, Sarah R.
Gepubliceerd in Cell Metab (2021)