Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy

The glucocorticoid receptor (GR) is a member of the nuclear receptor superfamily, which controls programs regulating cell proliferation, differentiation, and apoptosis. We have identified an unexpected role for GR in mitosis. We discovered that specifically modified GR species accumulate at the mito...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Matthews, Laura C., Berry, Andrew A., Morgan, David J., Poolman, Toryn M., Bauer, Kerstin, Kramer, Frederike, Spiller, David G., Richardson, Rachel V., Chapman, Karen E., Farrow, Stuart N., Norman, Michael R., Williamson, Andrew J. K., Whetton, Anthony D., Taylor, Stephen S., Tuckermann, Jan P., White, Michael R. H., Ray, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418855/
https://ncbi.nlm.nih.gov/pubmed/25847991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411356112
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