Pin1 promotes GR transactivation by enhancing recruitment to target genes

The glucocorticoid receptor (GR) is a ligand activated transcription factor, serving to regulate both energy metabolism and immune functions. Factors that influence cellular sensitivity to glucocorticoids (GC) are therefore of great interest. The N-terminal of the GR contains numerous potential prol...

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Autori principali: Poolman, Toryn M., Farrow, Stuart N., Matthews, Laura, Loudon, Andrew S., Ray, David W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
Soggetti:
Gene Regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794586/
https://ncbi.nlm.nih.gov/pubmed/23887939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt624
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