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A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response

The glucocorticoid receptor (GR) is essential for the stress response in mammals. We investigated potential non-transcriptional roles of GR in cellular stress response using fission yeast as a model.We surprisingly discovered marked heat stress resistance in yeast ectopically expressing human GR, wh...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ptushkina, Marina, Poolman, Toryn, Iqbal, Mudassar, Ashe, Mark, Petersen, Janni, Woodburn, Joanna, Rattray, Magnus, Whetton, Anthony, Ray, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608759/
https://ncbi.nlm.nih.gov/pubmed/28935859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09722-z
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