Glucocorticoids rapidly inhibit cell migration through a novel, non-transcriptional HDAC6 pathway

Glucocorticoids (GCs) act through the glucocorticoid receptor (GR, also known as NR3C1) to regulate immunity, energy metabolism and tissue repair. Upon ligand binding, activated GR mediates cellular effects by regulating gene expression, but some GR effects can occur rapidly without new transcriptio...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Kershaw, Stephen, Morgan, David J., Boyd, James, Spiller, David G., Kitchen, Gareth, Zindy, Egor, Iqbal, Mudassar, Rattray, Magnus, Sanderson, Christopher M., Brass, Andrew, Jorgensen, Claus, Hussell, Tracy, Matthews, Laura C., Ray, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295589/
https://ncbi.nlm.nih.gov/pubmed/32381682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.242842
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