Running on time: the role of circadian clocks in the musculoskeletal system

Por Dudek, Michal, Meng, Qing-Jun
Publicado em 2014

Ageing and osteoarthritis: a circadian rhythm connection

Por Gossan, Nicole, Boot-Handford, Ray, Meng, Qing-Jun
Publicado no Biogerontology (2014)

Circadian clocks and breast cancer

Por Blakeman, Victoria, Williams, Jack L., Meng, Qing-Jun, Streuli, Charles H.
Publicado no Breast Cancer Res (2016)

Lithium Impacts on the Amplitude and Period of the Molecular Circadian Clockwork

Por Li, Jian, Lu, Wei-Qun, Beesley, Stephen, Loudon, Andrew S. I., Meng, Qing-Jun
Publicado em 2012

GPR50 Interacts with TIP60 to Modulate Glucocorticoid Receptor Signalling

Por Li, Jian, Hand, Laura E., Meng, Qing-Jun, Loudon, Andrew S. I., Bechtold, David A.
Publicado em 2011

Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment

Por Williams, Jack, Yang, Nan, Wood, Amber, Zindy, Egor, Meng, Qing-Jun, Streuli, Charles H.
Publicado no J Cell Sci (2018)

Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development

Por Umemura, Yasuhiro, Koike, Nobuya, Ohashi, Munehiro, Tsuchiya, Yoshiki, Meng, Qing Jun, Minami, Yoichi, Hara, Masayuki, Hisatomi, Moe, Yagita, Kazuhiro
Publicado no Proc Natl Acad Sci U S A (2017)

The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor

Por Gossan, Nicole C., Zhang, Feng, Guo, Baoqiang, Jin, Ding, Yoshitane, Hikari, Yao, Aiyu, Glossop, Nick, Zhang, Yong Q., Fukada, Yoshitaka, Meng, Qing-Jun
Publicado em 2014

Gremlin-2 is a BMP antagonist that is regulated by the circadian clock

Por Yeung, Ching-Yan Chloé, Gossan, Nicole, Lu, Yinhui, Hughes, Alun, Hensman, James J., Bayer, Monika L., Kjær, Michael, Kadler, Karl E., Meng, Qing-Jun
Publicado em 2014

Ligand modulation of REV-ERBα function resets the peripheral circadian clock in a phasic manner

Por Meng, Qing Jun, McMaster, Andrew, Beesley, Stephen, Lu, Wei Qun, Gibbs, Julie, Parks, Derek, Collins, Jon, Farrow, Stuart, Donn, Rachelle, Ray, David, Loudon, Andrew
Publicado em 2008

Disrupted circadian clocks and altered tissue mechanics in primary human breast tumours

Por Broadberry, Eleanor, McConnell, James, Williams, Jack, Yang, Nan, Zindy, Egor, Leek, Angela, Waddington, Rachel, Joseph, Leena, Howe, Miles, Meng, Qing-Jun, Streuli, Charles H
Publicado no Breast Cancer Res (2018)

Cellular mechano-environment regulates the mammary circadian clock

Por Yang, Nan, Williams, Jack, Pekovic-Vaughan, Vanja, Wang, Pengbo, Olabi, Safiah, McConnell, James, Gossan, Nicole, Hughes, Alun, Cheung, Julia, Streuli, Charles H., Meng, Qing-Jun
Publicado no Nat Commun (2017)

Shared Ageing Research Models (ShARM): a new facility to support ageing research

Por Duran, Adele L., Potter, Paul, Wells, Sara, Kirkwood, Tom, von Zglinicki, Thomas, McArdle, Anne, Scudamore, Cheryl, Meng, Qing-Jun, de Haan, Gerald, Corcoran, Anne, Bellantuono, Ilaria
Publicado em 2013

The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis

Por Gossan, Nicole, Zeef, Leo, Hensman, James, Hughes, Alun, Bateman, John F, Rowley, Lynn, Little, Christopher B, Piggins, Hugh D, Rattray, Magnus, Boot-Handford, Raymond P, Meng, Qing-Jun
Publicado em 2013

Osteoarthritis-like pathologic changes in the knee joint induced by environmental disruption of circadian rhythms is potentiated by a high-fat diet

Por Kc, Ranjan, Li, Xin, Forsyth, Christopher B., Voigt, Robin M., Summa, Keith C., Vitaterna, Martha Hotz, Tryniszewska, Beata, Keshavarzian, Ali, Turek, Fred W., Meng, Qing-Jun, Im, Hee-Jeong
Publicado no Sci Rep (2015)

The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration

Por Dudek, Michal, Yang, Nan, Ruckshanthi, Jayalath PD, Williams, Jack, Borysiewicz, Elzbieta, Wang, Ping, Adamson, Antony, Li, Jian, Bateman, John F, White, Michael R, Boot-Handford, Raymond P, Hoyland, Judith A, Meng, Qing-Jun
Publicado no Ann Rheum Dis (2017)

The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

Por Dudek, Michal, Gossan, Nicole, Yang, Nan, Im, Hee-Jeong, Ruckshanthi, Jayalath P.D., Yoshitane, Hikari, Li, Xin, Jin, Ding, Wang, Ping, Boudiffa, Maya, Bellantuono, Ilaria, Fukada, Yoshitaka, Boot-Handford, Ray P., Meng, Qing-Jun
Publicado no J Clin Invest (2015)

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis

Por Pekovic-Vaughan, Vanja, Gibbs, Julie, Yoshitane, Hikari, Yang, Nan, Pathiranage, Dharshika, Guo, Baoqiang, Sagami, Aya, Taguchi, Keiko, Bechtold, David, Loudon, Andrew, Yamamoto, Masayuki, Chan, Jefferson, van der Horst, Gijsbertus T.J., Fukada, Yoshitaka, Meng, Qing-Jun
Publicado em 2014

Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2

Por Smyllie, Nicola J., Pilorz, Violetta, Boyd, James, Meng, Qing-Jun, Saer, Ben, Chesham, Johanna E., Maywood, Elizabeth S., Krogager, Toke P., Spiller, David G., Boot-Handford, Raymond, White, Michael R.H., Hastings, Michael H., Loudon, Andrew S.I.
Publicado no Curr Biol (2016)

Environmental Disruption of Circadian Rhythm Predisposes Mice to Osteoarthritis-Like Changes in Knee Joint

Por Kc, Ranjan, Li, Xin, Voigt, Robin M, Ellman, Michael B, Summa, Keith C, Vitaterna, Martha Hotz, Keshavarizian, Ali, Turek, Fred W, Meng, Qing-Jun, Stein, Gary S., van Wijnen, Andre J., Chen, Di, Forsyth, Christopher B, Im, Hee-Jeong
Publicado no J Cell Physiol (2015)