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Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development

Circadian clock oscillation emerges in mouse embryo in the later developmental stages. Although circadian clock development is closely correlated with cellular differentiation, the mechanisms of its emergence during mammalian development are not well understood. Here, we demonstrate an essential rol...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Umemura, Yasuhiro, Koike, Nobuya, Ohashi, Munehiro, Tsuchiya, Yoshiki, Meng, Qing Jun, Minami, Yoichi, Hara, Masayuki, Hisatomi, Moe, Yagita, Kazuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594651/
https://ncbi.nlm.nih.gov/pubmed/28827343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703170114
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