The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

Osteoarthritis (OA) is the most prevalent and debilitating joint disease, and there are currently no effective disease-modifying treatments available. Multiple risk factors for OA, such as aging, result in progressive damage and loss of articular cartilage. Autonomous circadian clocks have been iden...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Dudek, Michal, Gossan, Nicole, Yang, Nan, Im, Hee-Jeong, Ruckshanthi, Jayalath P.D., Yoshitane, Hikari, Li, Xin, Jin, Ding, Wang, Ping, Boudiffa, Maya, Bellantuono, Ilaria, Fukada, Yoshitaka, Boot-Handford, Ray P., Meng, Qing-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701559/
https://ncbi.nlm.nih.gov/pubmed/26657859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82755
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