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Cell-based inhibitor screening identifies multiple protein kinases important for circadian clock oscillations

Molecular oscillation of the circadian clock is based on E-box-mediated transcriptional feedback loop formed with clock genes and their encoding products, clock proteins. The clock proteins are regulated by post-translational modifications such as phosphorylation. We investigated the effects of a se...

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Detalhes bibliográficos
Publicado no:Commun Integr Biol
Main Authors: Kon, Naohiro, Sugiyama, Yasunori, Yoshitane, Hikari, Kameshita, Isamu, Fukada, Yoshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594307/
https://ncbi.nlm.nih.gov/pubmed/26478783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420889.2014.982405
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