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Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment

The circadian clock is an autonomous molecular feedback loop inside almost every cell in the body. We have shown that the mammary epithelial circadian clock is regulated by the cellular microenvironment. Moreover, a stiff extracellular matrix dampens the oscillations of the epithelial molecular cloc...

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Dettagli Bibliografici
Pubblicato in:J Cell Sci
Autori principali: Williams, Jack, Yang, Nan, Wood, Amber, Zindy, Egor, Meng, Qing-Jun, Streuli, Charles H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897718/
https://ncbi.nlm.nih.gov/pubmed/29361531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.208223
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