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Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment

The circadian clock is an autonomous molecular feedback loop inside almost every cell in the body. We have shown that the mammary epithelial circadian clock is regulated by the cellular microenvironment. Moreover, a stiff extracellular matrix dampens the oscillations of the epithelial molecular cloc...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Williams, Jack, Yang, Nan, Wood, Amber, Zindy, Egor, Meng, Qing-Jun, Streuli, Charles H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897718/
https://ncbi.nlm.nih.gov/pubmed/29361531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.208223
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