The Role of Multidrug Resistance Efflux Pumps in Cancer: Revisiting a JNCI Publication Exploring Expression of the MDR1 (P-glycoprotein) Gene

Por Gottesman, Michael M., Pastan, Ira H.
Publicado no J Natl Cancer Inst (2015)

A Mutant of 3T3 Cells with Cyclic AMP Metabolism Sensitive to Temperature Change

Por Willingham, Mark C., Carchman, Richard A., Pastan, Ira H.
Publicado em 1973

NEXT-GENERATION RECOMBINANT IMMUNOTOXINS FOR GLIOBLASTOMAS AND MELANOMAS TREATMENT

Por Kuan, Chien-Tsun, Pastan, Ira H., Bigner, Darell D.
Publicado em 2014

Anoctamin and transmembrane channel-like proteins are evolutionarily related

Por HAHN, YOONSOO, KIM, DONG SEON, PASTAN, IRA H., LEE, BYUNGKOOK
Publicado em 2009

Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases

Por Hahn, Yoonsoo, Bera, Tapan Kumar, Gehlhaus, Kristen, Kirsch, Ilan R., Pastan, Ira H., Lee, Byungkook
Publicado em 2004

Cell membrane-specific epitopes on CD30: Potentially superior targets for immunotherapy

Por Nagata, Satoshi, Ise, Tomoko, Onda, Masanori, Nakamura, Kazuyasu, Ho, Mitchell, Raubitschek, Andrew, Pastan, Ira H.
Publicado em 2005

Production and quality control assessment of a GLP-grade immunotoxin, D2C7-(scdsFv)-PE38KDEL, for a Phase I/II clinical trial

Por Chandramohan, Vidyalakshmi, Pegram, Charles N., Piao, Hailan, Szafranski, Scott E., Kuan, Chien-Tsun, Pastan, Ira H., Bigner, Darell D.
Publicado no Appl Microbiol Biotechnol (2016)

Tofacitinib Suppresses Antibody Responses to Protein Therapeutics in Murine Hosts()

Por Onda, Masanori, Ghoreschi, Kamran, Steward-Tharp, Scott, Thomas, Craig, O’Shea, John J., Pastan, Ira H., FitzGerald, David J.
Publicado em 2014

Antitumor efficacy of D2C7-(scdsFv)-PE38KDEL, a novel immunotoxin targeting EGFRwt and EGFRvIII, by convection-enhanced delivery in orthotopic brain tumor mouse models

Por Bao, Xuhui, Chandramohan, Vidyalakshmi, Keir, Stephen T, Pegram, Charles N, McLendon, Roger E, Kuan, Chien-Tsun, Pastan, Ira H, Bigner, Darell D
Publicado em 2013

EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells

Por Ochiai, Hidenobu, Archer, Gary E., Herndon, James E., Kuan, Chien-Tsun, Mitchell, Duane A., Bigner, Darell D., Pastan, Ira H., Sampson, John H.
Publicado em 2007

Recombinant anti-podoplanin (NZ-1) immunotoxin for the treatment of malignant brain tumors

Por Chandramohan, Vidyalakshmi, Bao, Xuhui, Kaneko, Mika Kato, Kato, Yukinari, Keir, Stephen T., Szafranski, Scott E., Kuan, Chien-Tsun, Pastan, Ira H., Bigner, Darell D.
Publicado em 2012

Affinity-matured recombinant immunotoxin targeting gangliosides 3′-isoLM1 and 3′,6'-isoLD1 on malignant gliomas

Por Piao, Hailan, Kuan, Chien-Tsun, Chandramohan, Vidya, Keir, Stephen T, Pegram, Charles N, Bao, Xuhui, Månsson, Jan-Eric, Pastan, Ira H, Bigner, Darell D
Publicado em 2013

Construction of an immunotoxin, D2C7-(scdsFv)-PE38KDEL, targeting EGFRwt and EGFRvIII for brain tumor therapy

Por Chandramohan, Vidyalakshmi, Bao, Xuhui, Keir, Stephen T., Pegram, Charles N., Szafranski, Scott E., Piao, Hailan, Wikstrand, Carol J., McLendon, Roger E., Kuan, Chien-Tsun, Pastan, Ira H., Bigner, Darell D.
Publicado em 2013

Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia

Por Haso, Waleed, Lee, Daniel W., Shah, Nirali N., Stetler-Stevenson, Maryalice, Yuan, Constance M., Pastan, Ira H., Dimitrov, Dimiter S., Morgan, Richard A., FitzGerald, David J., Barrett, David M., Wayne, Alan S., Mackall, Crystal L., Orentas, Rimas J.
Publicado em 2013

Preclinical Toxicity Evaluation of a Novel Immunotoxin, D2C7-(scdsFv)-PE38KDEL, Administered via Intracerebral Convection-Enhanced Delivery in Rats

Por Bao, Xuhui, Chandramohan, Vidyalakshmi, Reynolds, Randall P., Norton, John N., Wetsel, William C., Rodriguiz, Ramona M., Aryal, Dipendra K., McLendon, Roger E., Levin, Edward D., Petry, Neil A., Zalutsky, Michael R., Burnett, Bruce K., Kuan, Chien-Tsun, Pastan, Ira H., Bigner, Darell D.
Publicado no Invest New Drugs (2016)