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Cell membrane-specific epitopes on CD30: Potentially superior targets for immunotherapy

Because CD30 is highly expressed on Hodgkin's lymphoma and anaplastic large cell lymphoma, it is a promising target for immunotherapy. Soluble CD30, the extracellular domain of CD30 that is shed from the cells, can reduce the effects of CD30-targeting agents by competitive binding. In this stud...

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Bibliografiska uppgifter
Huvudupphovsmän: Nagata, Satoshi, Ise, Tomoko, Onda, Masanori, Nakamura, Kazuyasu, Ho, Mitchell, Raubitschek, Andrew, Pastan, Ira H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142388/
https://ncbi.nlm.nih.gov/pubmed/15905329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502975102
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